Wegovy GLP-1 Oral Pill vs. Pen

The first, and currently only, glucagon‑like peptide‑1 (GLP‑1) pill approved by the U.S. Food and Drug Administration for weight loss is now available by prescription.

With the recent approval of the oral Wegovy pill, patients seeking semaglutide for weight loss now have a needle‑free alternative to the injectable pen. Both options contain the same active ingredient and deliver similar weight loss benefits, but they differ in several important ways.

View this comparison chart to see the differences.

If you are interested in learning more about treatments for weight loss, discuss these options with your health care provider to determine if Wegovy is right for you. The right treatment will depend on your medical profile, lifestyle, personal preferences, medical history and insurance coverage, which may affect what’s accessible or affordable. Reviewing these factors with your care team can help you select the Wegovy formulation that fits your needs and supports your health goals.